[Re-sent] May 15, 2024

Hey - Hello. My name is Kathy and I'll be your server. On today's menu you'll find some tasty questions about Dementia and MS, a lovely pairing of DMTs, a side of smoldering MS, your choice of B-cell metabolism or a single drop of blood as a predictor of MS, a perfectly aged bottle of obesity drugs, and to finish your evening, a dessert of rising MS diagnoses.  I hope you'll enjoy your dining experience at Chez FUMS.🧡**I'm dedicating some time and energy 🥱 to building the 6-Pack's subscriber base. I'd so appreciate your help. I'd like to include some quotes from people who feel they've benefitted from the 6-Pack. If that describes YOU and you'd like to help me, please hit reply and send me your "testimonial" about how the 6-Pack helps you or how you've benefitted from the 6-Pack. Thanks in advance! Shall we take a gander 👀 at this week's happenings in MS?1.  I have been dealing with some pretty concerning symptoms lately: time distortion, cog fog, and a complete disconnect from recent events. Anytime we are dealing with cognitive function issues, I KNOW we all go there - "is this MS or dementia". Amiright? Scary stuff. I've had several - especially newly dx'ed MS'ers -  ask if MS can cause dementia. I saw this article and wanted to share it with you: Can MS Cause Dementia?2.  When did you start DMT and on which one did you start?? "People with MS who start treatment with a mild-to-moderate efficacy disease-modifying therapy (DMT) were more likely to switch to another DMT, an analysis of the German MS Registry finds. Starting a DMT between 2014 and 2017 was also a predictor of switching. Disease activity despite treatment was the most common reason to change DMTs.  Use of mild-to-moderate DMTs predicts switching to other DMTs3.  An abnormally active metabolism in immune B-cells can trigger the release of pro-inflammatory signaling molecules that drive further inflammation in MS, a study found. Treatments muting B-cell metabolism could ease symptoms. I L🧡VE the sound of that! Altered immune B-cell metabolism drives inflammation in MS4.  What if just one drop of blood could be a predictor of developing MS? 🤯  Think about it. Knowing that early on, pre-symptom development, having the potential to start aggressive therapy to stop it before it starts. It's so exciting for the future of this disease. But I'm getting ahead of myself. I'm such a dreamer. Read on friends: A Single Drop of Blood Could Soon Reveal Your Risk of Developing MS5.  With all the conversation of Ozempic, Wegovy and Mounjaro being used as weight loss drugs, I got curious about whether these drug might have any benefits for MS. Well - long-time MS writer Trevis Gleason just so happened to have written something just this week on this very topic. I'm adding psychic to my resume! 😉  Obesity Drugs and Multiple Sclerosis6.  Multiple Sclerosis Diagnoses Are Rising—And Doctors Don’t Know Why  The risk of an American developing MS is now roughly 1 in 333. 😳  I have my own theories (for instance, we are sitting inside in front of computers and phones rather than outside moving and soaking up those UVB rays that convert to Vitamin D). 🌞  What do YOU think? Do YOU have a theory as to why MS diagnoses are on the rise??? I'd love to hear them. 👂🏻Kathy Recommends:It's almost summer! Do you have plans for travel? Are you worried about traveling due to your disability or mobility challenges? I got choo: 

Travel for All has organized more than 5,000 vacations around the world for travelers with a variety of requirements, including cane users, slow walkers, hearing and vision impaired persons, travelers with complex health issues like dialysis and developmental disabilities, and wheelchair users. “As multiple sclerosis began to affect my own personal travel, I researched what resources could assist me with executing travel using my wheelchair,” says CEO Tarita Davenock. “I was shocked when I saw the lack of services.” Every trip Travel for All plans comes with an accessibility specialist. “We research and give our clients the pros and cons of any area in the world before planning the trip, so our client knows what to expect while they are in that destination,” says Davenock. “Meticulous planning and great attention to detail are the keystones of keeping our vacations safe.” Reach out to Travel for All today - and tell them FUMS sent you!**I interviewed Tarita for the FUMS Podcast in 2018! Here's where to listen: Travel Without Limits with Tarita Davenock 🎧

That's all folks. Let me know if you have any questions or if I can help you in any way. Otherwise, just keep saying FUMS!! 🧡Cheers -- KathyKathy Reagan YoungFounderFUMSP.S. Want to see the products that help me live life well with (and despite) MS?  Here you go: FUMS's Amazon Shop

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